Development of Memory Networks in Children
Our main research goals involve testing developmental effects in a wide variety of memory paradigms, such as recall and recognition, associative memory and emotional memory. We are also interested in the effects of cognitive control, executive functions, and growth in knowledge base on memory development.
Our studies use extensive behavioral assessments, neuroimaging protocols looking at the structure and the function of the brain, genetic information and longitudinal designs to allow multidimensional characterization of memory development.
This funded project and other research activities are aimed to collect structural and functional neuroimaging data that can be used to identify memory-related cortical activations and to correlate variability in the brain measures with that in cognitive functioning as the brain develops from childhood to adulthood.
Publications:
- Yu Q, McCall DM, Homayouni R, Tang L, Chen Z, Schoff D, Nishimura M, Raz S, Ofen N. Age-associated increase in mnemonic strategy use is linked to prefrontal cortex development. NeuroImage. 2018 Nov 01; 181 :162-169
- Kambara T, Brown EC, Jeong JW, Ofen N, Nakai Y, Asano E. Spatio-temporal dynamics of working memory maintenance and scanning of verbal information. Clin Neurophysiol. 2017 Jun;128(6):882-891. PMID: 28399442 PMCID: PMC5429980
- Tang, L., Shafer, A.T., Ofen, N.(2017). Prefrontal Cortex Contributions to the Development of Memory Formation, Cerebral Cortex, 2017,1-14. doi.org/10.1093/cercor/bhx200
- Yu, Q., Daugherty, A.M., Anderson, D.M., Nishimura, M, Brush, D., Hardwick, A., Lacey, W., Raz, S., Ofen, N.(2017). Socioeconomic status and hippocampal volume in children and young adults, Developmental Science, 2017;e12561. doi.org/10.1111/desc.12561
- Daugherty, A.M., Flinn, R., Ofen, N.(2017). Hippocampal CA3-dentate gyrus volume uniquely linked to improvement in associative memory from childhood to adulthood, NeuroImage, Volume 153, 75-85, doi: 10.1016/j.neuroimage.2017.03.047
For further publications, see:
ofenlab.wayne.edu/pubs/publications